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Friday, January 23, 2026

How to Prepare Your Immune System for Cold and Flu Season

By Dr. Cintara Bradley, Sonoran University of Health Sciences Clinical Care

As the weather cools and cold and flu season sets in, many people look for ways to stay healthy beyond the usual vitamin C and hand sanitizer routine. While quick fixes and over-the-counter immune “boosters” are everywhere, a sustainable, whole-body approach is key to building true immune resilience.

Choosing the Right Supplements

Wellness begins at the cellular level, so vitamins and micronutrients form the foundation of health. Vitamins C, D, and zinc are well-studied for immune support, and I recommend micronutrients year-round to prevent and shorten illness. Multivitamins that include vitamins A, B, C, and D, along with other micronutrients, help fortify immunity and support longevity. Adding omega-3s and a probiotic replenishes nutrients, strengthens the immune system, and boosts gut health.

Gut Health, Sleep, and Immune Function

About 70% of our immune system resides in the gut, where gut-associated lymphoid tissue produces immunoglobulins and other cells that help fight infections. When functioning properly, these defenses help stave off illness. Sleep deprivation disrupts the microbiome and increases gut inflammation, so prioritize 7–9 hours of quality sleep and regular exercise to maintain balance.

Daily Preventive Habits

Long-term wellness starts with habits. Turn off screens an hour before bed and practice stress-reducing rituals like a warm shower, journaling, or reading to prepare for restful sleep. Sunshine is also essential. Though days are shorter in fall and winter, aim for daily exposure by taking a walk during lunch or spending 20–30 minutes outside in the morning. Sunshine provides vitamin D, a key immunomodulator that improves aging and longevity, and mobilizes immune regulatory cells to fight infection.

Finally, focus on quality food. Ultra-processed foods strain the body’s repair systems and divert energy to digestion. Anti-inflammatory, whole foods equip the body with nutrients to thrive. Fiber supports gut health by increasing short-chain fatty acids (SCFAs), which improve gastrointestinal mucosal integrity, the health of colonocytes (colon cells), and immune function. Antioxidant-rich fruits like bananas, citrus, and berries, along with carotenoid-packed vegetables such as carrots, sweet potatoes, broccoli, peppers, kale, and spinach, strengthen immunity. Pair carotenoids with healthy fats like avocados, olive oil, nuts, and seeds for better absorption.

It’s important to be extra cautious during times where viruses are more active than others, however keeping your immune system strong year-round can greatly improve your chances of staying healthy no matter the season. Incorporating proper supplements, prioritizing gut health and rest, and fueling your body with nutrient-packed foods are all easy ways to keep your body’s defenses firing on all cylinders. At Sonoran University of Health Sciences’ Medical Center, we are prepared to help you battle through flu season, combining preventative measures with a whole-body approach that’s designed to assess potential health risks and address any root causes found.

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